The trailer for the new Dragon Ball movie -- titled Dragon Ball Super: Super Hero and slated to release in 2022 -- doesn't give much info on who the new villains are, but there are subtle hints for keen-eyed fans. We know it's an underground organization, and that they're targeting Goku, Vegeta, Piccolo, and Buu. Why they are targeting these four is as mysterious as their origins, but we may have some clues to their identity.
During the Dragon Ball Super: Super Hero trailer, we see a character drinking out of a cup with a certain red logo on it. This logo is the symbol of the Red Ribbon Army, a faction that was thought to have been disbanded after Goku fought them as a child. However, one of their scientists, Dr. Gero, returned to get revenge against Goku with the use of Androids. He created Androids 16, 17, and 18, as well as Cell. Though Androids 1-7 are mentioned, we never see them as they were deemed failures and thought to be dismantled.
The reveal of the Red Ribbon logo may hint at a return of Androids. The faction definitely has a vendetta against Goku, but why they would be targeting Vegeta, Piccolo, and Buu as well is unknown. The Dragon Ball Super: Super Hero trailer also revealed two characters named Gamma 1 and Gamma 2.
How they connect to the story is being kept secret, but it's possible they are a new version of Android developed by the Red Ribbon Army. We know they are working with the enemy, because they can be seen looking at a large screen showing the heroes while a man in a red suit speaks to someone off-camera. Gamma 2 can also be seen with a Red Ribbon Army patch on their left arm if the video is slowed down.
Whether Gamma 1 and Gamma 2 are Androids or not hasn't been disclosed, but given the RRA has canonically used Androids in other Dragon Ball media like the games, it isn't a hard theory to believe. It's very possible that their new scientists have taken Dr. Gero's work and reinvented the Androids with more modern programming. There's also the matter of the boy wearing a purple suit with an H on it drinking out of the cup with the Red Ribbon logo on it. Though his name and identity have yet to be revealed, it's possible he is an Android as well.
It's been a while since Dragon Ball fans have seen the Red Ribbon Army in non-game media. If they are using Android technology, it will be interesting to see how they've expanded on Dr. Gero's research and experiments. It's clear they've been working toward this for a while, seeing as the group was thought to have been disbanded since Goku was a child. Even Dr. Gero thought the Red Ribbon Army was no more -- his whole reason for going after Goku and creating the Androids in the first place. Dragon Ball Super: Super Hero is a story that's been in the making for almost 37 years. The Red Ribbon Army was one of the first major groups Goku fought against in the series, so it's only fitting that they have one last row with a new generation of Saiyans helping out.